Tumefactive demyelinating lesions: Characteristics of individual lesions, individual patients, or a unique disease entity?
نویسندگان
چکیده
منابع مشابه
Tumefactive demyelinating lesions: Characteristics of individual lesions, individual patients, or a unique disease entity?
Whether or not recurrent tumefactive demyelinating lesions are a unique form of CNS demyelinating disease or part of the continuum of multiple sclerosis is a question raised by the case report on which this commentary is based. Detailed review and immunopathologic study of biopsy material may not only confirm or refute a diagnosis of demyelinating disease, but potentially uncover unique feature...
متن کاملMagnetic Resonance Imaging Characteristics of Tumefactive Demyelinating Lesions
Tumefactive demyelinating lesions (TDLs) are often misdiagnosed as brain tumors. To identify imaging characteristics of TDLs for their proper diagnosis, their differences from malignant gliomas, etc., were investigated based on 3-Tesla magnetic resonance imaging (MRI) and MR spectroscopy data that was obtained from 5 patients diagnosed with TDLs in our hospital. MRI displayed a paraventricular ...
متن کاملProton MR spectroscopy of tumefactive demyelinating lesions.
BACKGROUND AND PURPOSE Tumefactive demyelinating lesions (TDLs) can simulate intracranial neoplasms in clinical presentation and MR imaging appearance, and surgical biopsy is often performed in suspected tumors. Proton MR spectroscopy has been applied in assessing various intracranial diseases and is increasingly used in diagnosis and clinical management. Our purpose was to determine if multivo...
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Whenever MRI imaging depicts typical small, ovoid, well-circumscribed T2 hyperintense lesions scattered across periventricular, iuxtacortical and infratentorial white matter along with a clinical scenario highly suggestive of inflammatory-demyelinating disease of CNS (CNS IID), multiple sclerosis (MS) diagnosis is straightforward. Nevertheless, the expanding role of MRI in MS evaluation is para...
متن کاملCase Series: tumefactive demyelinating lesions: a diagnostic challenge.
T umefactive demyelinating lesion (TDL) is defined as a solitary de myelin ating lesion greater than 2 cm. Mass effect and contrast enhancement on neuroimaging make it difficult to distinguish this type of lesion from high-grade gliomas. Multiple sclerosis (MS) accounts for most cases of TDL. Even in patients with established MS, an atypical manifestation of a large lesion can suggest concurren...
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ژورنال
عنوان ژورنال: Multiple Sclerosis Journal
سال: 2015
ISSN: 1352-4585,1477-0970
DOI: 10.1177/1352458515603801